Table 5.
Association of all derived haplotypes as a whole in each gene with baseline characteristics of study subjects.
| Characteristics | ApoB gene | PCSK9 gene | ||||
|---|---|---|---|---|---|---|
| Global statistics | P | Simulated P | Global statistics | P | Simulated P | |
| Age | 13.08 | 0.442 | 0.269 | 2.57 | 0.462 | 0.451 |
| Gender | 24.27 | 0.029 | 0.069 | 6.00 | 0.112 | 0.104 |
| BMI | 8.93 | 0.778 | 0.497 | 1.46 | 0.692 | 0.698 |
| Duration of diabetes | 11.72 | 0.468 | 0.307 | 1.28 | 0.734 | 0.759 |
| Hypertension | 104.82 | <0.001 | 0.001 | 1.12 | 0.773 | 0.794 |
| Smoking | 13.81 | 0.387 | 0.283 | 0.78 | 0.854 | 0.862 |
| TC | 12.14 | 0.516 | 0.257 | 1.37 | 0.712 | 0.709 |
| HbA1C | 17.48 | 0.178 | 0.101 | 0.29 | 0.963 | 0.962 |
| HCY | 18.18 | 0.151 | 0.057 | 1.61 | 0.656 | 0.651 |
| TG | 9.51 | 0.733 | 0.371 | 0.44 | 0.933 | 0.950 |
| HDLC | 6.61 | 0.921 | 0.656 | 2.43 | 0.488 | 0.507 |
| LDLC | 13.25 | 0.429 | 0.210 | 2.69 | 0.443 | 0.407 |
BMI, body mass index; TC, total cholesterol; HbA1C, hemoglobin A1c; HCY, homocysteine; TG, triglyceride; HDLC, high-density lipoprotein cholesterol; LDLC, low-density lipoprotein cholesterol.