Figure 2.

Distributed white matter tract integrity and cardiovascular fitness. (A) The absolute value of partial regression coefficients for each tract that remained non-zero after training the initial elastic net model predicting residualized VO₂Max. (B) Scatterplot of the correlation between model-predicted and actual sex-adjusted estimated VO₂Max (centered and scaled) within the set-aside test subset (R² = 0.028, p = 0.003). (C) Absolute value of the average partial regression coefficients for each tract from all iterations of the ensemble modeling. (D) Distribution of R²s gathered from the subsequent ensemble modeling using 1,000 iterations of the elastic net model (Ensemble R² = 0.013, 25th−75th quartile = 0.005–0.02).