FIGURE 2.

BL pre-administration decreased levels of serum biochemical markers and inflammatory cytokines. Rats were pre-administered with 1 × 10⁸ CFU twice a day (HS + BL group) for 7 days or PBS (HS + PBS group), and blood samples were collected 3 h after HS onset and at the same time for the control group rats. Serum biochemical marker levels of ALT (A), AST (B), BU (C), CK (D), and CREA (E) and inflammatory cytokines TNF-α (F), IL-1β (G), and IL-6 (H) are presented as means ± SEM, n = 10 per group. ^nsP > 0.05, ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001. ALT, alanine aminotransferase; AST, aspartate aminotransferase; BU, blood urea; CK, creatine kinase; CREA, creatinine.