Table 2.

Model parameters and variables.

Parameter or variable	Definition	Source
${\varphi }_T\left(\overline{x},t\right)$	Tumor cell volume fraction	Measured from DWI
${\varphi }_E\left(\overline{x},t\right)$	Enhancing tumor volume fraction	Measured from DWI
${\varphi }_N\left(\overline{x},t\right)$	Non-enhancing tumor volume fraction	Assigned to fixed value
kp,T, kp,E kp,N	Proliferation rates	Calibrated
βNE, βEN	Competition terms	Set to 4 and 1
θT,, θE,, θN	Carrying capacity	Calibrated, θN set to 0.16
DT,w, DE,w, DN,w, DT,g, DE,g, DN,g	Diffusion coefficients in absence of mechanically coupling for white and gray matter	Calibrated
Gw	Shear modulus for white matter	2.7 kPa47
Gg	Shear modulus for gray matter	3.1 kPa47
V	Poisson’s ratio	Set to 0.45
λ1	Coupling constants	Calibrated
λ2	Coupling constants	Set to 1
SFRT,min	Surviving fraction following radiotherapy	Calibrated
SFCT,min	Surviving fraction following chemotherapy	Calibrated