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. 2021 Apr 19;11:8474. doi: 10.1038/s41598-021-87895-4

Figure 1.

Figure 1

Patients exposed to Zika virus during fetal life and born with microcephaly express distinct inflammatory profile in cerebrospinal fluid: Left panel: Data were log-transformed and z-score normalized. A heatmap was built to describe the overall expression profile of the inflammatory markers measured in cerebrospinal fluid (CSF) in each study group labeled according to the experimental group indicated by distinct colors (gray control, blue Zika virus without microcephaly and red Zika virus with microcephaly). Right panel: Average fold-difference values in expression of inflammatory markers in CSF from children with zika virus exposure, zika virus exposure that developed microcephaly and control group are described (log-transformed values). Red bars infer markers which values tended to be higher in the disease groups whereas blue bars denote markers which concentrations were higher in the control group.