Table 3.

Univariate survival analysis of OS and DFS after allo-HSCT $\left(\overline{x}\pm s\right)$ (N = 55).

Variables	No. of patients	OS		DFS	P
		Rate/%	P value	Rate/%	P value
Age			0.719		0.549
≤ 25	27	14.007 ± 2.052		12.263 ± 2.044
> 25	28	18.621 ± 2.625		16.713 ± 2.596
Sex			0.906		0.591
Male	34	17.679 ± 2.380		16.791 ± 2.388
Female	21	15.2 ± 2.418		12.248 ± 2.297
Primary disease			0.187		0.296
ALL	23	20.761 ± 2.804		18.291 ± 2.888
AML	32	12.988 ± 1.886		11.918 ± 1.829
Gene mutation and/or fusion gene			0.872		0.891
Yes	41	18.087 ± 2.164		15.929 ± 2.16
No	14	14.571 ± 2.985		13.98 ± 2.886
Abnormal chromosome			0.984		0.45
Yes	21	14.681 ± 2.369		11.695 ± 2.286
No	34	17.774 ± 2.366		16.922 ± 2.363
Disease status at HSCT			0.433		0.392
CR1	41	18.756 ± 2.151		17.366 ± 2.163
CR2 and CR3	6	8.767 ± 3.407		8.767 ± 3.407
NR	8	13.813 ± 3.613		10.044 ± 3.128
MRD			0.030		0.005
Positive	18	10.194 ± 2.318		8.069 ± 1.971
Negative	37	20.422 ± 2.215		18.957 ± 2.246
Sex of donor–recipient			0.585		0.649
Identical	42	17.467 ± 2.172		16.697 ± 2.177
Different	13	13.777 ± 2.284		9.885 ± 2.145
Donor–recipient ABO compatibility			0.277		0.209
Compatible	25	12.976 ± 2.148		11.272 ± 2.077
Incompatible	30	19.607 ± 2.492		17.694 ± 2.517
Conditioning regimen			0.406		0.872
TBI/Cy-based	36	14.072 ± 1.846		13.386 ± 1.849
Bu/Cy-based	19	19.942 ± 3.119		15.622 ± 3.074
Donor source			0.298		0.545
Haploid donors	25	13.048 ± 2.137		12.192 ± 2.11
Unrelated donors	30	19.547 ± 2.504		16.765 ± 2.515
HLA matching			0.541		0.707
HLA-match donors	23	16.048 ± 2.303		14.388 ± 2.286
HLA-mismatched donors	32	16.863 ± 2.443		15.1 ± 2.41
GVHD prophylaxis			0.514		0.691
Control	14	12.914 ± 2.813		12.3 ± 2.705
Ruxolitinib	41	18.641 ± 2.17		16.554 ± 2.178
aGVHD			0.003		0.008
Yes	16	8.675 ± 2.377		8.258 ± 2.225
No	39	21.008 ± 2.133		18.785 ± 2.207
Grade II–IV aGVHD			0.002		0.003
Yes	11	7.173 ± 2.575		6.718 ± 2.312
No	44	20.277 ± 2.040		18.307 ± 2.088
cGVHD			0.003		< 0.001
Yes	16	26.9 ± 2.396		26.806 ± 2.448
No	39	11.967 ± 1.748		9.877 ± 1.608
Hemorrhagic cystitis			0.356		0.992
Yes	28	15.886 ± 2.569		15.789 ± 2.585
No	27	16.537 ± 2.134		13.521 ± 2.111
Pulmonary infection			0.105		0.445
Yes	37	15.7 ± 2.278		14.795 ± 2.262
No	18	18.533 ± 2.401		14.839 ± 2.573
Intestinal infection			0.703		0.41
Yes	16	13.125 ± 2.436		10.2 ± 2.046
No	39	18.503 ± 2.252		17.056 ± 2.258
EBV infection			0.282		0.205
Yes	4	13.25 ± 1.516		13.25 ± 1.516
No	51	17.286 ± 1.958		15.09 ± 1.926
CMV infection			0.279		0.193
Yes	43	15.986 ± 2.114		14.621 ± 2.09
No	12	19.1 ± 2.468		16.369 ± 2.598