Table 1.
Patient characteristics (n = 479)*.
| Characteristics | Frequency | Missing values |
|---|---|---|
| Number (%) | Numbers | |
| Age (median, IQR) | 58.0 (46.1, 71.1) | 0 |
| Females | 242 (50.5) | 0 |
| Risk factors | ||
| Provoked by surgery° | 95 (19.9) | 0 |
| Non-surgical transient risk factor° | 107 (22.3) | 0 |
| Unprovoked VTE° | 265 (55.3) | 0 |
| Active cancer° | 12 (2.5) | 0 |
| Pregnancy | 6 (1.3) | 0 |
| Contraceptive use | 50 (10.4) | 6 |
| Travel | 34 (7.1) | 0 |
| Immobilization | 40 (8.4) | 6 |
| Inflammation | 64 (13.4) | 7 |
| Previous VTE | 91 (19.0) | 0 |
| Cardiovascular disease | 115 (24.0) | 5 |
| Heart failure | 6 (1.3) | 6 |
| Known thrombophilia | 19 (4.0) | 7 |
| Venous insufficiency | 31 (6.5) | 8 |
| Varicosis | 22 (4.6) | 177 |
| Residual thrombosis† | 144 (30.1) | 60 |
| Smoking | 107 (22.3) | 29 |
| Family history | 140 (29.2) | 14 |
| Elevated D-dimer& | 112 (23.4) | 122 |
| Elevated CRP& | 109 (22.8) | 174 |
| Elevated FVIII& | 65 (13.6) | 157 |
| Elevated Villalta score$ | 78 (16.3) | 96 |
*
Observation period 2,231 patient-years; median 3.1 years; five patients were lost to follow-up because they moved abroad;
°
mutually exclusive groups;
†
determined 1 week before intended stop of anticoagulation treatment;
&
1 month after stopping anticoagulation treatment;
$
at 6 months.