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. 2021 Apr 6;9:617589. doi: 10.3389/fcell.2021.617589

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Copyright © 2021 Li, Li, Xie and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristics of human bone marrow–derived mesenchymal stem cell (hBMSC)–derived exosomes. (A) Representative images of hBMSC-derived exosomes under transmission electron microscopy. Scale bar: 500 and 200 nm. (B) Size distributions of hBMSC-derived exosomes determined by dynamic light scattering. (C) Positive expression of CD9, CD63, and CD81 in isolated exosomes by western blot. β-Actin was used as the control for western blot. Fib-lys, the total cell lysate of human fibroblasts; Fib-exo, the exosomes from human fibroblasts; Msc-exo, the exosomes from human bone marrow–derived mesenchymal stem cells.