Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 19;12:2327. doi: 10.1038/s41467-021-22572-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a Kaplan–Meier curves of HNSCC TCGA cohort stratified by STING mRNA expression (low vs high). b Kaplan–Meier curves of patients stratified by total STING expression (low vs high). c Representative images of TMA spot from b stained for DAPI, cytokeratin (tumor mask), and STING. Arrows indicated STING staining in both compartments (tumor and stroma). d Representative images of TMA spots illustrating grouping of TMA specimens into four groups based upon compartmental STING expression. Each patient specimen was stained once due to lack of material, with images representative of their respective groups: b (from entire patient cohort) or d (groups defined in e). e Kaplan–Meier curves of patients stratified by four groups identified in d. All statistical analysis was performed by log-rank testing with P-values as indicated in graphs. Scale bars are 100 μm in c and d.