Radiological and biomechanical analyses of the 4-cm femur defect reconstruction with three-dimensional-printed porous Ti6A14V implants. (A) (i-iii) Radiographs at 1, 3, and 6 months after implantation, respectively. (iv-vi) Computed tomography images at 1, 3, and 6 months after implantation, respectively. Blue arrows denote newly formed bone in the defect sites or on the implant's outer surface. (vii) Radiographic scores of the groups (n = 4). (B) (i-iii) Three-dimensional reconstruction images of the 1-, 3-, and 6-month groups after sacrifice, respectively (gray denotes titanium alloy, and green represents newly formed bone). (ⅳ) Quantitative results of the bone volume fractions in the peri-implant and intraporous regions of the implants in each group (n = 4).