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. 2021 Mar 19;24:487–511. doi: 10.1016/j.omtn.2021.03.011

Figure 3.

Figure 3

Comparison of apoptosis and anoikis

The lack of ECM contact or the engagement with inappropriate ECM leads to the activation of anoikis either by death receptors (extrinsic pathway) or mitochondria (intrinsic pathway).