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. 2021 Apr 5;26:100994. doi: 10.1016/j.bbrep.2021.100994

Table 11.

Pharmacokinetic and toxicological properties of the compounds of C. digyna for good oral bioavailability.

Compounds M.W(g/mol) HBA HBD Log P Ames Toxicity Carcinogens
Isointricatinol 302.32 5 2 2.58 Non-Ames toxic Non-carcinogenic
Isobonducellin 284.31 4 2 2.17 Non-Ames toxic Non-carcinogenic
Z-eucomine 298.33 4 2 1.77 Non-Ames toxic Non-carcinogenic

M.W = molecular weight, HBA = Hydrogen bond acceptor, HBD = Hydrogen bond donor, Log P = Lipophilicity.