Table 11.
Pharmacokinetic and toxicological properties of the compounds of C. digyna for good oral bioavailability.
| Compounds | M.W(g/mol) | HBA | HBD | Log P | Ames Toxicity | Carcinogens |
|---|---|---|---|---|---|---|
| Isointricatinol | 302.32 | 5 | 2 | 2.58 | Non-Ames toxic | Non-carcinogenic |
| Isobonducellin | 284.31 | 4 | 2 | 2.17 | Non-Ames toxic | Non-carcinogenic |
| Z-eucomine | 298.33 | 4 | 2 | 1.77 | Non-Ames toxic | Non-carcinogenic |
M.W = molecular weight, HBA = Hydrogen bond acceptor, HBD = Hydrogen bond donor, Log P = Lipophilicity.