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. 2021 Apr 5;26:100994. doi: 10.1016/j.bbrep.2021.100994

Table 3.

Impact of the methanol extract of C. digyna stems on castor oil incited intraluminal fluid accumulation in mice.

Treatment Dose, route (p.o) MWSIC (g) % of inhibition MVSIC (mL) % of inhibition
Group-Ⅰ 1% tween 80-10 mL/kg 0.60 ± 0.02 0.48 ± 0.02
Group-Ⅱ Loperamide-3 mg/kg 0.17 ± 0.09*** 71.66 0.13 ± 0.01*** 72.91
Group-Ⅲ MECD-50 mg/kg 0.53 ± 0.01* 11.66 0.44 ± 0.02 8.33
Group-Ⅳ MECD-100 mg/kg 0.38 ± 0.02*** 36.67 0.30 ± 0.02** 37.50
Group-Ⅴ MECD-200 mg/kg 0.27 ± 0.01*** 55.00 0.22 ± 0.01*** 54.16
Group-Ⅵ MECD-400 mg/kg 0.17 ± 0.02*** 71.66 0.17 ± 0.01*** 64.58

The values are expressed as mean ± SEM (n = 6); One-way analysis of variance (ANOVA) suggested by Dunnett's test. Significant (*p < 0.05, **p < 0.01, ***p < 0.001) compared with the control sample. MECD = methanol extract of C. digyna. MWSIC = mean weight of the small intestinal content, MVSIC = mean volume of the small intestinal content.