Table 4.
Impact of the stem's extracts of C. digyna on intestinal transit in mice.
| Treatment | Dose, route (p.o) | Total intestinal length (cm) | Distance moved by the charcoal meal (cm) | Peristaltic index (%) | % of inhibition |
|---|---|---|---|---|---|
| Group-Ⅰ | 1% tween 80-10 mL/kg | 53.42 ± 2.02 | 38.87 ± 1.80 | 72.76 | – |
| Group-Ⅱ | Loperamide- 3 mg/kg | 49.67 ± 0.67 | 5.51 ± 0.77*** | 11.09 | 84.75 |
| Group-Ⅲ | MECD-50 mg/kg | 50.00 ± 1.83 | 32.47 ± 1.50* | 63.87 | 12.21 |
| Group-Ⅳ | MECD-100 mg\kg | 50.00 ± 1.77 | 23.93 ± 1.03** | 47.46 | 34.77 |
| Group-Ⅴ | MECD-200 mg/kg | 51.67 ± 1.40 | 13.02 ± 1.27*** | 36.81 | 49.40 |
| Group-Ⅵ | MECD-400 mg/kg | 50.17 ± 1.49 | 6.73 ± 0.64*** | 13.14 | 76.10 |
The narrated data were presented as Mean ± SEM (n = 6); One-way analysis of variance (ANOVA) followed by Dunnett's multiple comparison test; *p < 0.05, **p < 0.01, ***p < 0.001 were considered significant compared to the control sample. MECD = methanol extract of C. digyna.