Table 2.
Descriptive statistics of seminal pro-inflammatory cytokines in the population studied
| Cytokine (pg/ml) | Mean (SD) | Median (range) | Percentile (25-75) | Fertile men | Infertile men |
|---|---|---|---|---|---|
| IFN-γ | 731.92 ±1279.12 | 180.25 (0-7406) | 0-951.5 | 0 (0-130)a | 593 (192-1665)d |
| IL-1β | 327.42 ±736.88 | 28 (0-3985.33) | 0-198.41 | 0.70 (0.01-9)b | 5.66 (0.1-334.8)b |
| IL-6 | 224.23 ±500.77 | 31.8 (0-2994.8) | 0-205.8 | 11.98 (2.5-102)b | 48.91 (6.9-2634)b |
| TNF-α | 0.9457 ±6.63 | 0 (0-43.5) | 0-0 | 2.76 (0.55-10.3)b | 18.42 (0.8-360)b |
| IL-8 | 1477.61 ±5087.01 | 336.64 (0-31950) | 199.12-336.64 | 441.84 (215.4-767)b | 1975.34 (186.9-6754)b |
| IL-4 | 43.88 ±52.63 | 27.5 (0-212.5) | 7.18-71.87 | 12.6 ±3.8c | 8.4 ±3.9c |
| IL-10 | 16.06 ±92.34 | 0 (0-617) | 0-0 | 2.81e | 5.2 (2.7-7.7)f |
Concentration of cytokines reported by aPolitch et al., 2007, bMoretti et al., 2008, cOmu et al., 1999, dSeshadri et al., 2009, eJiang et al. 2016, fMartínez-Prado and Camejo, 2009 for comparison. IFN-γ – interferon-γ, TNF-α – tumor necrosis factor-α, IL-4 – interleukin-4, IL-1β – interleukin-1β, IL-6 – interleukin-6, IL-8 – interleukin-8. Values are median (range) in pg/ml in all results, except the reference values of Omu et al., 1999, which are mean ±SD.