Table 1.
Characteristics of study subjects
| Characteristic | No. (n = 1108) |
|---|---|
| Age (years) | 61.1 ± 11.0 (41 to 89) |
| Sex (F/M) | 461/647 |
| Education (years) | 9.8 ± 4.4 |
| CM-MMSE | 28.2 ± 1.9 |
| MoCA | 23.8 ± 4.0 |
| *APOE ε4 (carriers/non-carriers) | 161/800 |
| *CSF Aβ42 (pg/ml) | 167.6 ± 79.5 |
| *CSF Aβ40 (pg/ml) | 5981.8 ± 2728.5 |
| *CSF tau (pg/ml) | 171.3 ± 76.1 |
| *CSF p-tau (pg/ml) | 36.8 ± 9.1 |
| Healthy lifestyle factors (n, %) | |
| No current smoking | 888 (80.1%) |
| No or moderate drinking | 951 (85.8%) |
| Regular physical activity | 275 (24.8%) |
| Absence of social isolation | 868 (78.3%) |
| No. of healthy lifestyle factors (n, %) | |
| 0 | 9 (0.8%) |
| 1 | 84 (7.6%) |
| 2 | 302 (27.3%) |
| 3 | 558 (50.4%) |
| 4 | 155 (14.0%) |
Summarized as mean ± standard deviation (SD) for continuous data and count for categorical data. Abbreviations: CSF, cerebrospinal fluid; MMSE, Mini-Mental State Examination; p-tau, phosphorylated tau
* Data were missing for CSF Aβ42 (n = 162, 14.6%), CSF Aβ40 (n = 198, 17.9%), CSF tau (n = 92, 8.3%), CSF p-tau (n = 90, 8.1%), and APOE ε4 statues (n = 147, 13.3%)