Table 3.
Correlation between biochemical and inflammatory markers in NMOSD patients and control group
| NMOSD | control | |||||||
|---|---|---|---|---|---|---|---|---|
| Ln. IL-6 (pg/ml) | Ln.IL-17A(pg/ml) | Ln. IL-6 (pg/ml) | Ln.IL-17A(pg/ml) | |||||
| rb | P-value | R | P-value | rb | P-value | r | P-value | |
| Ln.insulin (μU/L) | 0.32 | 0.03a | 0.19 | 0.15 | −0.05 | 0.75 | −0.02 | 0.81 |
| FBS (mg/dL) | 0.11 | 0.54 | 0.003 | 0.98 | 0.07 | 0.66 | 0.16 | 0.10 |
| Ln.TG (mg/dL) | 0.34 | 0.02a | 0.16 | 0.23 | 0.32 | 0.04a | 0.34 | 0.001a |
| Ln.HDL (mg/dL) | −0.27 | 0.08 | −0.02 | 0.88 | −0.03 | 0.83 | −0.06 | 0.56 |
| LDL (mg/dL) | 0.05 | 0.74 | 0.02 | 0.86 | 0.11 | 0.51 | −0.008 | 0.93 |
| Chol. (mg/dL) | 0.003 | 0.98 | 0.03 | 0.84 | 0.16 | 0.34 | 0.10 | 0.32 |
| Ln.AST (U/L) | 0.12 | 0.44 | 0.19 | 0.18 | −0.02 | 0.89 | 0.11 | 0.26 |
| Ln.ALT (U/L) | −0.08 | 0.62 | −0.03 | 0.81 | 0.06 | 0.73 | −0.11 | 0.28 |
a After adjusting with BMI, age and sex, there was constant significant correlation
br: Pearson’s correlation was applied to determine the correlation between circulating markers and inflammatory markers in NMOSD patients and controls
ALT alanine aminotransferase, SAT serum agglutination test, Chol total cholesterol, HDL high-density lipoprotein cholesterol, IL-6 interleukin −6, IL-17A interleukin-17A, LDL low-density lipoprotein, Ln natural log, TG triglyceride