Table 2.
Clinical data for the GDM patients and normal controls in the validation cohort
| Characteristics | GDM(n = 57) | HC(n = 63) | p-value |
|---|---|---|---|
| Maternal age (year) | 33.54 ± 4.62 | 31.90 ± 3.85 | 0.04 |
| Gestational weeks of delivery | 38.30 ± 8.14 | 38.84 ± 2.94 | 0.77 |
| Pre-pregnancy BMI (kg/m2) | 26.03 ± 1.98 | 26.18 ± 1.63 | 0.11 |
| Fasting glucose (mmol/L) | 4.45 ± 0.54 | 3.99 ± 0.34 | < 0.001 |
| 1 h plasma glucose (mmol/L) | 9.67 ± 1.27 | 7.40 ± 1.19 | < 0.001 |
| 2 h plasma glucose (mmol/L) | 8.62 ± 1.11 | 6.04 ± 1.17 | < 0.001 |
| GHBA1c (%) | 5.40 ± 0.47 | 5.25 ± 0.47 | 0.08 |
| Neonatal birth weight (Kg) | 2.96 ± 0.58 | 3.13 ± 0.50 | 0.08 |
| Hemoglobin (g/L) | 118.10 ± 13.88 | 117.40 ± 12.73 | 0.79 |
| ALT(U/L) | 14.40 ± 6.32 | 15.22 ± 6.56 | 0.49 |
| AST(U/L) | 21.09 ± 4.69 | 20.43 ± 4.39 | 0.43 |
| Triglycerides (mmol/L) | 3.65 ± 1.44 | 3.69 ± 2.39 | 0.92 |
| Total cholesterol (mmol/L) | 6.39 ± 1.17 | 6.44 ± 1.02 | 0.81 |
| HDL-C (mmol/L) | 1.81 ± 0.32 | 1.80 ± 0.36 | 0.94 |
| LDL-C (mmol/L) | 3.65 ± 0.78 | 368.00 ± 0.66 | 0.85 |
| TBA (umol/L) | 3.44 ± 3.69 | 3.19 ± 1.80 | 0.63 |
| Abortion history | |||
| Yes | 29 (50.88%) | 15 (23.81%) | 0.02 |
| No | 28 (29.12%) | 48 (76.19%) | |
| Gestational hypertension (yes/total) | |||
| Yes | 7 (12.28%) | 1 (1.59%) | 0.02 |
| No | 50 (87.72%) | 62 (98.41%) | |
| Mode of delivery | |||
| Eutocous | 30 (52.63%) | 46 (73.02%) | 0.02 |
| Anesthesia operation | 27 (47.37%) | 17 (26.98%) | |
| Fetal distress | |||
| Yes | 18 (31.58%) | 14 (22.22%) | 0.25 |
| No | 39 (68.42%) | 49 (77.78%) | |
| Shoulder dystocia | |||
| Yes | 1 (1.75%) | 0 (0.00%) | 0.29 |
| No | 56 (98.25%) | 63 (100.00%) | |
| Preterm birth | |||
| Yes | 4 (7.55%) | 7 (11.11%) | 0.43 |
| No | 53 (92.45%) | 56 (88.89%) | |
| Postpartum bleeding | |||
| Yes | 5 (8.77%) | 5 (7.94%) | 0.87 |
| No | 52 (91.23%) | 58 (92.06%) | |