Table 2.

Maternal cardiac data in reduced uterine perfusion pressure rat model

	Sham (n ≥ 6)	RUPP (n ≥ 4)	p value
Maternal body weight (before surgery), g	338.6 ± 17.5	379.5 ± 4.87	0.084
Maternal heart weight, g	1.02 ± 0.05	1.22 ± 0.01	0.008**
Heart: Body weight, %	0.304 ± 0.01	0.323 ± 0.005	0.303
Embryo resorption (%)	2.38 ± 1.51	11.22 ± 3.06	0.04*
Embryo weight, g	1.68 ± 0.025	1.61 ± 0.02	0.04
Placental weight, g	0.41 ± 0.009	0.39 ± 0.006	0.047
Heart rate, bpm	369.3 ± 4.8	398.8 ± 3.7	0.0006***
Systolic BP, mmHg	112.6 ± 1.3	127.8 ± 1.9	< 0.0001***
Diastolic BP, mmHg	87.6 ± 1.7	104.0 ± 1.8	< 0.0001***
MABP, mmHg	100.9 ± 1.5	116.7 ± 1.7	< 0.0001***
Stroke volume, μl	215.0 ± 4.326	230.0 ± 13.26	0.304
Cardiac output, mL/min	79 ± 3	85 ± 5	0.067
Ejection fraction, %	82 ± 2	78 ± 2	0.233
Fractional shortening, %	52 ± 2	49 ± 2	0.236
Corrected LV mass, mg	600 ± 14	706 ± 68	0.037*
LV anterior wall systolic, mm	2.9 ± 0.12	2.9 ± 0.11	0.672
LV anterior wall diastolic, mm	1.5 ± 0.04	1.8 ± 0.17	0.152
LV posterior wall systolic, mm	2.8 ± 0.14	2.9 ± 0.09	0.303
LV posterior wall diastolic, mm	1.6 ± 0.05	1.6 ± 0.11	0.994

BP, blood pressure; LV, left ventricular, MABP, mean arterial blood pressure; RUPP, reduced uterine perfusion pressure

Unpaired Student’s t-test or Mann-Whitney test depending on data distribution; *p < 0.05, ***p < 0.001