Table 3.
Pre to Post Treatment Neurocognitive Raw Score Performance
| Domain | Test | N | Pre-Mean (SD) | Post-Mean (SD) | t; p-value |
|---|---|---|---|---|---|
| Verbal Learning & Memory | HVLT Learning | 241 | 25.7 (4.7) | 25.6 (4.9) | 0.25; 0.803 |
| HVLT Delayed Recall | 241 | 9.2 (2.3) | 9.2 (2.2) | −0.13; 0.899 | |
| Visual Learning & Memory | BVMT Delayed Recall | 242 | 8.2 (3.0) | 8.8 (2.8) | −4.0; <0.001***† |
| BVMT Learning | 242 | 4.5 (2.1) | 4.0 (2.0) | 3.0; 0.003**† | |
| Visuospatial Processing | Block Design | 242 | 37.5 (11.8) | 40.2 (12.5) | −5.3; <.001***† |
| Abstract Reasoning | Matrix | 205 | 17.5 (4.7) | 17.9 (4.5) | −1.9; 0.063 |
| Attention/Working Memory | Digit Span | 189 | 19.2 (3.8) | 19.7 (4.0) | −2.1; 0.037*† |
| Information Processing Speed | SDMT | 234 | 49.7 (10.2) | 51.4 (9.7) | −3.8; <0.001***† |
| Stroop Color Word | 240 | 37.8 (9.3) | 39.5 (9.4) | −4.2; <0.001***† | |
| Visual Detection/Perseveration | CPT Hit RT | 232 | 460.9 (62.6) | 471.3 (66.2) | −3.1; 0.002**† |
| CPT Detectability | 232 | 0.82 (0.39) | 0.95 (0.45) | −5.3; <0.001***† | |
| CPT Variability | 232 | 9.9 (9.1) | 9.1 (9.9) | 1.1; 0.266 | |
| CPT Perseverations | 67 | 2.5 (7.8) | 1.9 (9.7) | 0.4; 0.677 | |
| Visual Categorization & Problem Solving | DKEFS Time 1st Sort | 244 | 7.8 (7.3) | 19.0 (14.0) | −15.3; <0.001***† |
| DKEFS Total Correct Sorts | 243 | 9.3 (2.5) | 8.7 (2.8) | 3.8; <0.001***† | |
| DKEFS Total Incorrect Sorts | 243 | 2.9(2.9) | 2.5 (2.8) | 1.6; 0.112† | |
| DKEFS Correct Over Attempted (All) | 243 | 0.80 (0.15) | 0.81 (0.16) | −0.7; 0.481 | |
| DKEFS Correct Over Attempted (Set 1) | 244 | 0.79 (0.20) | 0.85 (0.18) | −4.4; <0.001*** | |
| Decision Making & Planning | IGT Net Total Score | 182 | 20.7 (29.6) | 25.9 (32.2) | −2.0; 0.045* |
*
significant at <0.05
**
significant at <0.01
***
significant at <0.001
†
significant in sensitivity analysis group at <0.050