Table I.
Influence of coinfection on the risk of death for severe COVID-19 patients with comorbidities
| Comorbidity/risk factor | Total (negative/positive culture) |
OR (95% CI) | P-value | R2 | |
|---|---|---|---|---|---|
| Discharged | Death | ||||
| Cardiovascular disease (N = 136) | 62 (52/10) | 74 (23/51) | 11.53 (4.99–26.63) | <0.0001 | 0.28 |
| Diabetes (N = 82) | 38 (28/10) | 44 (14/30) | 6.00 (2.29–15.69) | 0.0002 | 0.17 |
| Obesity (N = 56) | 18 (12/06) | 38 (10/28) | 5.60 (1.66–18.92) | 0.0042 | 0.15 |
| Invasive ventilation (N = 114) | 24 (14/10) | 90 (25/65) | 3.63 (1.14–11.49) | 0.0005 | 0.07 |
| Asthma (N = 23) | 11 (8/03) | 12 (5/7) | 3.73 (0.65–21.58) | 0.1500 | 0.10 |
| COPD (N = 7) | 03 (1/02) | 04 (2/2) | 0.5 (0.02–11.09) | 0.6830 | 0.03 |
| HIV (N = 8) | 04 (2/2) | 04 (0/4) | Undefineda | 0.1266 | 0.33 |
| Hypothyroidism (N = 6) | 04 (3/1) | 02 (0/2) | Undefineda | 0.1138 | 0.50 |
COPD, chronic obstructive pulmonary disease; HIV, human immunodeficiency virus.
Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using stratified univariate analysis.
R2 was calculated using regression model.
a
Undefined because OR could not be calculated with a zero cell.