Table 1.
A comparison of patient factors between those who were placed on VV ECMO for ARDS secondary to COVID-19 infection versus those with ARDS secondary to confirmed influenza infection.
| Patients with COVID-19 (n = 32) | Patients with Influenza (n = 28) | p value | |
|---|---|---|---|
| Patient Factors | |||
| Age (years) | |||
| Mean (SD) | 47.8 (10.3) | 41.2 (12.8) | 0.033 |
| Sex: n (%) | |||
| Male | 25 (78.1) | 16 (57.1) | 0.08 |
| Female | 7 (21.9) | 12 (42.9) | |
| BMI | |||
| Mean (SD) | 35.1 (7.8) | 37.1 (10.1) | 0.4 |
| Race: n (%) | |||
| Latino | 17 (53.1) | 2 (7.1) | <0.001 |
| African-American | 6 (18.8) | 5 (17.9) | |
| Caucasian | 9 (28.1) | 18 (64.3) | |
| Other | 0 (0.0) | 3 (10.7) | |
| Diabetic? | |||
| Yes: n (%) | 16 (50.0) | 3 (10.7) | 0.001 |
| Charleson Comorbidity Index: | |||
| Median (IQR) | 1 (0–2) | 0 (0–1.5) | 0.4 |
| Clinical Status | |||
| Number of Days from Symptom Onset to Cannulation | |||
| Mean (SD) | 16.2 (8.3) | 8.5 (4.4) | <0.001 |
| Use of Non-invasive Positive-Pressure (NIPPV) Ventilation Prior to Cannulation | |||
| Yes: n (%) | 25 (78.1) | 14 (50.0) | 0.023 |
| Mean Days on Non-Invasive Ventilation: Mean (SD) | 3.3 (4.1) | 0.78 (1.8) | 0.004 |
| Proned Prior to Cannulation? | |||
| Yes: n (%) | 26 (81.3) | 1 (3.6) | <0.001 |
| Number of Days from ICU Admission to Cannulation | |||
| Mean (SD) | 8.7 (7.2) | 1.8 (2.2) | <0.001 |
| Number of Days of Intubation Prior to Cannulation | |||
| Mean Days (SD) | 4.5 (4.3) | 1.5 (1.7) | <0.001 |
| P:F Ratio at Cannulation | |||
| Mean (SD) | 69.3 (19.9) | 58.5 (33.8) | 0.1 |
| Murray Score at Cannulation | |||
| Score 0 | 0 (0.0) | 0 (0.0) | 1.0 |
| Score 0.1–2.5 | 0 (0.0) | 0 (0.0) | |
| Score > 2.5 | 32 (100.0) | 32 (100.0) | |
|
Labs at Cannulation: Mean (SD) |
|||
| Serum pH | 7.31 (0.11) | 7.23 (0.12) | 0.006 |
| Fibrinogen | 695 (249) | 419 (207) | <0.001 |
| D-dimer | 3628 (5277) | 3503 (5287) | 0.9 |