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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Pancreas. 2020 Nov-Dec;49(10):1297–1306. doi: 10.1097/MPA.0000000000001690

FIGURE 2.

FIGURE 2.

Neutrophil gelatinase–associated lipocalin rescues cerulein-induced cell death in mouse acinar cells. A, MTT assay for evaluating cerulein dose response in pancreatic acinar cell viability during a 12-hour treatment. B, Viability of acinar cells in the presence of 20 μM cerulein along with 800 and 1600 ng/mL levels of rmNGAL for 12 hours as measured by MTT assay. C, D, Effect of rmNGAL in preventing cerulein-induced acinar cell death as demonstrated by annexin V/PI live dead staining. E, The rmNGAL blocks cerulein-induced acinar cell death by modulating PARP expression as demonstrated by Western blot analysis. *P < 0 0.05, **P < 0.01, ***P < 0.001, ns, not significant.