Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The central volume of distribution Vc of an isosmotic colloid approximates to the free flowing plasma, while the Vc of an isotonic intravenous crystalloid infusion includes the whole of the intravascular space. The tissue volume of distribution Vt of a crystalloid infusion is limited to the expansile tissues, and is much less than the total extracellular fluid (ECF) volume.
