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Repurposing FDA-approved drugs for SARS-CoV-2 through cellular screening. (A) Summary of methodology used in this paper. (B) Screening for FDA-approved small molecule therapeutics for activities in suppressing SARS-CoV-2 replication in Vero E6 cells. Dose–response curves in the suppression of SARS-CoV-2 replication in Vero E6 cells and cytotoxicity for simeprevir (C) and remdesivir (D) are shown. Data points in all plots represent mean ± S.E.M. For all data points, n = 3 replicates.
