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. Author manuscript; available in PMC: 2021 Jun 2.
Published in final edited form as: Sci Transl Med. 2020 Dec 2;12(572):eabb5413. doi: 10.1126/scitranslmed.abb5413

Figure 1. Axial T2 FLAIR (T2 FLAIR), diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) MRI assessment of participants post-therapy.

Figure 1.

MRI abnormalities were localized at the sites of the catheter tips, where there is the highest concentration of the administered vector. A-D. Examples of T2 FLAIR. A. Participant V5, 1 day post-administration; B. V4, 6 months; C. V3, 12 months; D. V2, 18 months. E. Example of DWI, participant V4, 6 months. F. Example of ADC, participant V2, 18 months. Yellow arrows identify the abnormalities. See Table 4 for the complete dataset of T2 FLAIR, DWI and ADC abnormalities observed.