TABLE 4.
MNI Coordinates (in mm) of Local Maxima in Regions Showing BMI-Related Decreases in Intrinsic Functional Connectivity With Each Seed at Rest
| Seed | Region | Maximum z Score | x | y | z | 
|---|---|---|---|---|---|
| Left lateral orbitofrontal cortex | Left thalamus | 3.64 | −10 | −10 | 14 | 
| Right ventromedial prefrontal cortex | 3.91 | 32 | 56 | 4 | |
| Right nucleus accumbens | 3.21 | 14 | 18 | −8 | |
| Medial ACC | 3.16 | 0 | 34 | 22 | |
| Right orbitofrontal cortex | Right caudate | 4.11 | 16 | 18 | 12 | 
| Left paracingulate gyrus | 3.91 | −4 | 50 | 0 | |
| Left amygdala | 3.86 | −28 | −6 | −16 | |
| Right ACC | 3.63 | 4 | 40 | 8 | |
| Left ventromedial prefrontal cortex | 3.56 | −10 | 50 | −6 | |
| Right nucleus accumbens | 3.41 | 14 | 18 | −8 | |
| Medial posterior cingulate cortex | 3.24 | −4 | −36 | 38 | |
| Medial precuneus | 3.05 | −4 | −58 | 18 | |
| Left dorsomedial prefrontal cortex | Right putamena | 3.44 | 30 | 6 | −2 | 
| Left dorsomedial prefrontal cortex | 3.43 | −10 | 66 | 14 | |
| Right dorsomedial prefrontal cortex | 3.20 | 22 | 44 | 34 | |
| Right insula | 3.14 | 40 | −6 | 8 | |
| Medial posterior cingulate | 3.10 | 0 | −42 | 26 | |
| Right palliduma | 2.96 | 16 | 6 | 0 | |
| Left medial orbitofrontal cortex | Right ACC | 3.04 | 10 | 42 | 18 | 
| Right putamen | 2.77 | 22 | 8 | −10 | |
| Right superior frontal gyrus | 3.03 | 24 | 40 | 32 | |
| Right nucleus accumbens | 3.07 | 12 | 20 | −6 | |
| Left hippocampus | Medial ACC | 3.64 | −4 | 32 | 22 | 
| Medial paracingulate gyrus | 3.17 | 10 | 46 | 12 | |
| Ventromedial prefrontal cortex | 3.14 | −4 | 48 | −10 | 
MNI = Montreal Neurological Institute; BMI = body mass index; ACC = anterior cingulate cortex.
Regions met a cluster threshold of z > 2.3 and p < .05.
Denotes regions that showed BMI-related differences in functional connectivity with a given seed both at rest and during the visual food cue task.