TABLE 5.

Indirect Effect of BMI on Overall IGT Performance and on Change in IGT Performance From the First to the Final Block of the Task Operating Through Resting-State Seed-to-ROI Connectivity Values

	B	SE	95% ULCI	95% LLCI
Mediating effects on overall igt performance
Right orbitofrontal cortex
Left paracingulate gyrus	−0.191	0.086	−0.402	−0.050
Left ventromedial prefrontal cortex	−0.178	0.090	−0.397	−0.037
Medial posterior cingulate cortex	−0.170	0.086	−0.377	−0.034
Medial anterior cingulate cortex	−0.108	0.064	−0.282	−0.017
Right nucleus accumbens	−0.232	0.092	−0.449	−0.075
Left dorsomedial prefrontal cortex
Right pallidum	−0.178	0.099	−0.411	−0.021
Mediating effects on change in IGT performance
Left lateral orbitofrontal cortex
Medial anterior cingulate cortex	−0.345	0.181	−0.820	−0.081
Left thalamus	−0.022	0.010	−0.045	−0.005
Right nucleus accumbens	−0.283	0.168	−0.731	−0.036
Right ventromedial prefrontal cortex	−0.442	0.185	−0.861	−0.134
Right orbitofrontal cortex
Left ventromedial prefrontal cortex	−0.266	0.160	−0.673	−0.030
Left medial orbitofrontal cortex
Medial anterior cingulate cortex	−0.212	0.145	−0.631	−0.021
Right ventral striatum	−0.407	0.187	−0.886	−0.130

BMI = body mass index; IGT = Iowa Gambling Task; LLCI = lower limit of confidence interval; ULCI = upper limit of confidence interval.

Confidence intervals were computed using bias-corrected bootstrapping with 5000 samples. Seeds with which ROI connectivity values were not associated with IGT performance are not included in the table.