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. 2021 Apr 19;47(6):109. doi: 10.3892/ijmm.2021.4942

Figure 4.

Figure 4

Expression levels of NFKBIZ and PTEN are positively correlated. (A) NFKBIZ expression was significantly positively correlated with PTEN expression according to the Gene Expression Profiling Interacting Analysis database. (B and C) PTEN expression was increased in transfected T24 and 5637 cells overexpressing NFKBIZ. (D) Representative IHC images of NFKBIZ and PTEN expression in human bladder cancer tissues (magnification, ×200; scale bar, 50 µm). (E) Representative IHC images of PTEN expression in nude mice tumor tissues in the pc-NFKBIZ and pc-NC groups. **P<0.01 vs. NC. NC, negative control; NFKBIZ, NF-κB inhibitor ζ; IHC, immunohistochemistry; TPM, transcripts per million.