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. 2021 Apr 19;47(6):109. doi: 10.3892/ijmm.2021.4942

Figure 6.

Figure 6

Overexpression of NFKBIZ induces BC cell proliferation by regulating the PTEN/PI3K/Akt signaling pathway in BC cells. (A) Representative western blot images and quantitative analyses of related proteins, including (B) p-PI3K/PI3K, (C) p-AKT/AKT and (D) p-mTOR/mTOR in transfected T24 and 5637 cells overexpressing NFKBIZ. **P<0.01 vs. NC. (E) Representative western blot images and quantitative analyses of related proteins, including PTEN, p-PI3K/PI3K, p-AKT/AKT and p-mTOR/mTOR in transfected (F) T24 and (G) 5637 cells overexpressing NFKBIZ and after VO treatment. *P<0.05; **P<0.01. VO, VO-OHpic trihydrate; NC, negative control; NFKBIZ, NF-κB inhibitor ζ; p, phosphorylated; BC, bladder cancer.