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. 2021 Apr 16;47(6):105. doi: 10.3892/ijmm.2021.4938

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Knockdown of DNAJC12 inhibits the proliferation of lung cancer cells. HCS and MTT assays were used to determine the effects of DNAJC12 on A549 and NCI-H1975 cell proliferation. (A and B) Representative images of the HCS assay using A549 cells with/without DNAJC12 knockdown (A) and the statistical result (B). The relative cell number was analyzed using a one-way ANOVA. ^***P<0.001. (C and D) MTT assay was used to demonstrate that DNAJC12 knockdown inhibited the proliferation of (C) A549 and (D) NCI-H1975 cells with/without DNAJC12 knockdown. The relative cell number was analyzed using a one-way ANOVA. ^***P<0.001. DNAJC12, DnaJ heat shock protein family (Hsp40) member C12; HCS, high-content screening.