Figure 1.

Hypothetical pathogenesis of COVID-19. The X-axis is the number of days after SARS-CoV-2 infection, and it is divided into three phases according to the above conjecture. The Y-axis is the trend of T cells, B cells, inflammatory factors, d-dimer and viral load in patients. (A) The trend of each indicator in COVID-19 patients with severe type. (B) The trend of each indicator in COVID-19 patients with severe type after LWMH and IVIG therapy. The shaded areas represent the recommended intervention times for LMWH and IVIG treatment.[1] IVIG: intravenous immunoglobulin; LWMH: low molecular weight heparin.