Table 1.
Demographics and baseline characteristics of study participants.
| Variable | HDs (n = 9) | Total (n = 28) | Mild (n = 9) | Moderate (n = 10) | Severe (n = 9) | P value |
|---|---|---|---|---|---|---|
| Characteristics | ||||||
| Age (years) | 38.0 (35.0–42.0) | 45.0 (34.8–59.0) | 39.8 (27.5–54.5) | 41.9 (32.0–54.8) | 61.1 (43.5–78.5) | 0.020∗ |
| Sex | 0.265 | |||||
| Male | 6 | 17 | 4 | 8 | 5 | |
| Female | 3 | 11 | 5 | 2 | 4 | |
| Days from illness | NA | 4.0 (3.0–6.8) | 4.0 (2.5–4.5) | 4.0 (3.8–5.3) | 7.0 (3.5–10.0) | 0.153 |
| Exposure to Wuhan | NA | 16 | 7 | 5 | 4 | 0.306 |
| Any comorbidity | 0 | 6 | 0 | 2 | 4 | 0.071 |
| Hypertension | 0 | 5 | 0 | 1 | 4 | 0.035∗ |
| Diabetes | 0 | 3 | 1 | 1 | 1 | 0.996 |
| Malignancy | 0 | 1 | 0 | 0 | 1 | 0.335 |
| Chronic liver disease | 0 | 1 | 0 | 1 | 0 | 0.393 |
| Signs and symptoms | ||||||
| Fever (°C) | 0.152 | |||||
| <37.3 | NA | 1 | 1 | 0 | 0 | |
| 37.3–38.0 | NA | 10 | 5 | 4 | 1 | |
| 38.1–39.0 | NA | 15 | 2 | 5 | 8 | |
| >39.0 | NA | 2 | 1 | 1 | 0 | |
| Cough | 0 | 16 | 4 | 6 | 6 | 0.619 |
| Expectoration | 0 | 9 | 1 | 3 | 5 | 0.128 |
| Myalgia or fatigue | 0 | 13 | 3 | 2 | 8 | 0.007∗ |
| Sore throat | 0 | 2 | 0 | 1 | 1 | 0.598 |
| Shortness of breath | 0 | 6 | 0 | 1 | 5 | 0.009∗ |
| Chest pain | 0 | 4 | 0 | 0 | 4 | 0.007∗ |
| Diarrhea | 0 | 1 | 1 | 0 | 0 | 0.335 |
Categorical variables are presented as number. Continuous variables are shown as median (interquartile range). P values indicate the comparison between the mild, moderate, and severe groups, and were calculated by the Fisher's exact test or ANOVA, as appropriate.
HDs: Healthy donors; NA: Not applicable.
∗
P < 0.05.