Table 2.
PD-1 gene polymorphism vs. TB incidence
| TB patients | Controls | ORc（95% CI） | ORa#（95% CI） | ||||
|---|---|---|---|---|---|---|---|
| n | % | n | % | ||||
| rs2227982 | GG | 128 | 25.45 | 131 | 26.52 | 1 (reference) | 1 (reference) |
| GA | 274 | 54.47 | 267 | 54.05 | 1.050 (0.781–1.412) | 1.036 (0.762–1.407) | |
| AA | 101 | 20.08 | 96 | 19.43 | 1.077 (0.743–1.560) | 1.065 (0.724–1.567) | |
| GA + AA | 375 | 74.55 | 363 | 73.48 | 1.057 (0.797–1.403) | 1.043 (0.778–1.399) | |
| rs36084323 | AA | 143 | 28.43 | 122 | 24.70 | 1 (reference) | 1 (reference) |
| AG | 260 | 51.69 | 264 | 53.44 | 0.840 (0.625–1.130) | 0.820 (0.603–1.113) | |
| GG | 100 | 19.88 | 108 | 21.86 | 0.790 (0.549–1.137) | 0.768 (0.526–1.120) | |
| AG + GG | 360 | 71.57 | 372 | 75.3 | 0.826 (0.623–1.094) | 0.805 (0.601–1.077) | |
| rs7568402 | GG | 223 | 44.33 | 270 | 54.66 | 1 (reference) | 1 (reference) |
| GA | 233 | 46.32 | 195 | 39.47 | 1.447 (1.115–1.876) | 1.434 (1.100–1.869)* | |
| AA | 47 | 9.34 | 29 | 5.87 | 1.962 (1.195–3.221) | 1.891 (1.141–3.135)* | |
| GA + AA | 280 | 55.66 | 224 | 45.34 | 1.513 (1.179–1.943) | 1.493 (1.158–1.926)* | |
#Multivariate logistic regression model was used to adjust the covariates of sex, age, marital status, educational background, BMI, smoking status, alcohol drinking, tea drinking and BCG vaccination.
*P < 0.05.