Table 5.
Bi-variate and multivariable binary logistic regression analyses of variables with individual DD status among HIV-positive adults (18–65 years old) attending ART clinics at FHCSH, Northwest Ethiopia, 2019 (n = 352)
| Variable | DD | Crude | Adjusted | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| High | Lowa | Odds ratios (95 % confidence intervals) | P-value | Odds ratios (95 % confidence intervals) | P-value | |||||
| Sex | <0⋅001 | |||||||||
| Male | 136 | 61 | 2⋅50 | 1⋅62 | 3⋅88 | |||||
| Female | 73 | 82 | Reference | |||||||
| Age category (years) | 0⋅050 | |||||||||
| 18–24 | 8 | 9 | Reference | |||||||
| 25–34 | 60 | 59 | 1⋅14 | 0⋅41 | 3⋅17 | |||||
| 35–44 | 99 | 50 | 2⋅23 | 0⋅81 | 6⋅12 | |||||
| 45–54 | 35 | 18 | 2⋅19 | 0⋅72 | 6⋅63 | |||||
| 55–65 | 7 | 7 | 1⋅13 | 0⋅27 | 4⋅64 | |||||
| Religion | 0⋅041 | |||||||||
| Christian | 190 | 138 | Reference | |||||||
| Muslim | 19 | 5 | 2⋅76 | 1⋅01 | 7⋅57 | |||||
| Residence | 0⋅38 | |||||||||
| Urban | 181 | 119 | 1⋅30 | 0⋅72 | 2⋅36 | |||||
| Rural | 28 | 24 | Reference | |||||||
| Educational status | <0⋅001 | |||||||||
| No formal education | 37 | 52 | Reference | |||||||
| Primary education | 32 | 29 | 1⋅55 | 0⋅81 | 2⋅98 | |||||
| Secondary and above | 140 | 62 | 3.17 | 1.89 | 5.32 | |||||
| Marital status | 0⋅001 | |||||||||
| Married | 152 | 77 | Reference | |||||||
| Divorced | 23 | 24 | 0⋅49 | 0⋅26 | 0⋅92 | |||||
| Single | 20 | 15 | 0⋅68 | 0⋅33 | 1⋅39 | |||||
| Widowed | 14 | 27 | 0⋅26 | 0⋅13 | 0⋅53 | |||||
| Employment status | 0⋅001 | 0⋅001 | ||||||||
| Self-employed | 123 | 62 | 3⋅47 | 1⋅60 | 7⋅51 | 4⋅60 | 1⋅72 | 12⋅27 | ||
| Government employee | 59 | 37 | 2⋅79 | 1⋅23 | 6⋅33 | 1⋅51 | 0⋅51 | 4⋅50 | ||
| Daily labourer | 15 | 23 | 1⋅14 | 0⋅44 | 2⋅99 | 0⋅94 | 0⋅27 | 3⋅30 | ||
| Unemployed | 12 | 21 | Reference | Reference | ||||||
| Family size | 0⋅28 | |||||||||
| ≤4 | 28 | 43 | Reference | |||||||
| ≥5 | 181 | 100 | 1⋅26 | 0⋅82 | 1⋅94 | |||||
| Head of household | <0⋅001 | |||||||||
| Yes | 28 | 43 | 2⋅78 | 1⋅63 | 4⋅75 | |||||
| No | 181 | 100 | Reference | |||||||
| Source of food | 0⋅66 | |||||||||
| Purchase | 181 | 126 | 1⋅15 | 0⋅60 | 2⋅18 | |||||
| Farm | 28 | 17 | Reference | |||||||
| Quintiles of wealth index | <0⋅001 | <0⋅001 | ||||||||
| Lowest quintile | 22 | 52 | Reference | Reference | ||||||
| Second quintile | 34 | 31 | 2⋅59 | 1⋅29 | 5⋅20 | 4⋅33 | 1⋅72 | 10⋅89 | ||
| Middle quintile | 45 | 27 | 3⋅94 | 1⋅98 | 7⋅85 | 4⋅40 | 1⋅71 | 11⋅31 | ||
| Fourth quintile | 58 | 17 | 8⋅06 | 3⋅87 | 16⋅82 | 6⋅60 | 2⋅36 | 18⋅48 | ||
| Highest quintile | 50 | 16 | 7⋅39 | 3⋅48 | 15⋅67 | 9⋅45 | 3⋅34 | 26⋅77 | ||
| Smoke cigarettes | 0⋅001 | |||||||||
| No | 169 | 142 | Reference | |||||||
| Yes | 40 | 1 | 33⋅61 | 4⋅56 | 247⋅55 | |||||
| Drink alcohol | 0⋅010 | |||||||||
| No | 142 | 115 | Reference | |||||||
| Yes | 67 | 28 | 1⋅94 | 1⋅17 | 3⋅21 | |||||
| Chew khat | 0⋅005 | |||||||||
| No | 185 | 142 | Reference | |||||||
| Yes | 24 | 1 | 18⋅42 | 2⋅46 | 137⋅80 | |||||
| Follow media (TV/radio/magazine, etc.) | 0⋅002 | |||||||||
| No | 45 | 52 | Reference | |||||||
| Yes | 164 | 91 | 2⋅08 | 1⋅30 | 3⋅35 | |||||
| WHO clinical stage of the disease | 0⋅039 | |||||||||
| Stage I (T-1) | 83 | 79 | Reference | |||||||
| Stage II (T-2) | 83 | 42 | 1⋅88 | 1⋅16 | 3⋅05 | |||||
| Stage III | 42 | 21 | 1⋅90 | 1⋅04 | 3⋅50 | |||||
| Stage IV | 1 | 1 | 0⋅95 | 0⋅06 | 15⋅48 | |||||
| Last CD4 count (cell/mm3) | <0⋅001 | <0⋅001 | ||||||||
| <200 | 38 | 40 | Reference | Reference | ||||||
| 200–349 | 81 | 16 | 5⋅33 | 2⋅66 | 10⋅69 | 8⋅08 | 2⋅93 | 22⋅29 | ||
| >350 | 90 | 87 | 1⋅09 | 0⋅64 | 1⋅86 | 0⋅67 | 0⋅26 | 1⋅71 | ||
| Duration of ART (months) | 0⋅37 | |||||||||
| ≤24 | 21 | 9 | 1⋅74 | 0⋅77 | 3⋅95 | |||||
| 25–48 | 47 | 29 | 1⋅21 | 0⋅71 | 2⋅05 | |||||
| ≥ 49 | 141 | 105 | Reference | |||||||
| ART regimen category | <0⋅001 | <0⋅001 | ||||||||
| First line | 185 | 104 | 2⋅89 | 1⋅65 | 5⋅07 | 4⋅49 | 2⋅19 | 9⋅21 | ||
| Second line | 24 | 39 | Reference | Reference | ||||||
| Co-trimoxazole prophylaxis | <0⋅001 | <0⋅001 | ||||||||
| No | 190 | 105 | 3⋅62 | 1⋅99 | 6⋅60 | 6⋅36 | 2⋅54 | 15⋅88 | ||
| Yes | 19 | 38 | Reference | Reference | ||||||
| Those who had nutritional counselling at a health institution | 0⋅017 | 0⋅032 | ||||||||
| No | 24 | 30 | Reference | Reference | ||||||
| Yes | 185 | 113 | 2⋅05 | 1⋅14 | 3⋅68 | 2⋅36 | 1⋅08 | 5⋅16 | ||
| Food preferences | 0⋅029 | 0⋅022 | ||||||||
| No | 181 | 111 | 1⋅86 | 1⋅07 | 3⋅26 | 2⋅42 | 1⋅14 | 5⋅13 | ||
| Yes | 28 | 32 | Reference | 1⋅00 | ||||||
| Household food insecurity status | <0⋅001 | <0⋅001 | ||||||||
| Food insecure | 49 | 85 | Reference | Reference | ||||||
| Food secure | 160 | 58 | 4⋅79 | 3⋅01 | 7⋅60 | 3⋅51 | 1⋅85 | 6⋅67 | ||
The forward stepwise elimination binary logistic regression model was run adjusting for the variables significant at P < 0⋅20 in the unadjusted model (bi-variate) which included variables shown in the table.
The reference category is low DD.