Table 5.

Clinical laboratory urinalysis results of dogs before and 4 months after diet supplementation with vitamin D3 (n 8) or HyD^® (n 10)

		Supplementation
		Vitamin D3		HyD®		Vitamin D3 v. HyD®
		Pre-trial	4 months	Pre-trial	4 months	Pre-trial P	4 months P
Specific gravity	Mean Range	1⋅032 [1⋅012–1⋅064]	1⋅032 [1⋅005–1⋅053]	1⋅032 [1⋅004–1⋅059]	1⋅038 [1⋅015–1⋅054]	0⋅98	0⋅61
Glucose	Negative (n)	7	8	10	10	nd*	nd
	≥ Trace (n)	0	0	0	0
Bilirubin	Negative/1+ (n)	7	8	9	9	1⋅00	1⋅00
	≥2+ (n)	0	0	1	1
Ketones	Negative/trace (n)	7	8	10	10	nd	nd
	> Trace (n)	0	0	0	0
Heme	Negative/trace (n)	7	8	10	9	nd	1⋅00
	≥1+ (n)	0	0	0	1
pH	Median Range	6⋅0 [5⋅5–7⋅5]	8⋅5 [5⋅5–8⋅5]	6⋅5 [5⋅5–8⋅5]	6⋅8 [5⋅5–8⋅5]	0⋅49	0⋅26
Protein by dipstick	Negative (n)	6	5	10	9	0⋅41	0⋅27
	≥1+ (n)	1	3	0	1
Urobilinogen	0⋅2	7	8	10	10	nd	nd
(EU†/dL)	>0⋅2	0	0	0	0
Leucocyte‡/hpf§	None/1–3 (n)	6	7	9	6	1⋅00	0⋅31
	>3 (n)	1	1	1	4
Erythrocyteǁ/hpf	None/rare (n)	7	7	10	9	nd	1⋅00
	≥1 (n)	0	1	0	1
Bacteria/hpf	None (n)	7	8	10	9	nd	1⋅00
	Few (n)	0	0	0	1
Transitional Cells/lpf¶	None	None	None	None	None	nd	nd
Squamous Cells/lpf	None to 1–5 (n)	7	8	10	9	nd	1⋅00
	>5 (n)	0	0	0	1
Casts/lpf	None (n)	7	8	10	9	nd	1⋅00
	Rare (n)	0	0	0	1
Crystals/lpf	None (n)	6	5	8	7	1⋅00	1⋅00
	Moderate/many (n)	1	3	2	3
	Struvite (n)	1	3	2	2
	Other (n)	0	0	0	1a

^*Not determined because of lacking observation in one category.

^†Ehrlich units.

^‡Leucocytes.

^§High-power field.

^ǁErythrocytes.

^¶Low-power field.

^aOne dog with ‘many struvites and moderate calcium oxalate dehydrate’ which had very concentrated urine.