Table 3.

Multiple regression results for the relationship between reaction time z-score, mood disorder group and serum CRP level quintile before and after adjusting for confounders.

	Unadjusted model		Fully adjusted modela
	Coefficient (95% CI)	p-Value	Coefficient (95% CI)	p-Value
Reaction time z-scoreb
Serum CRP level quintile
2	0.002 (−0.018 to 0.023)	0.830	0.007 (−0.014 to 0.028)	0.512
3	−0.019 (−0.040 to 0.001)	0.067	0.001 (−0.021 to 0.022)	0.963
4	−0.030 (−0.051 to −0.009)	0.004	0.004 (−0.017 to 0.026)	0.696
5	−0.089 (−0.110 to −0.068)	<0.001	−0.030 (−0.052 to −0.008)	0.007
Bipolar disorder type I	−0.111 (−0.196 to −0.025)	0.011	−0.064 (−0.152 to 0.024)	0.156
Bipolar disorder type II	−0.042 (−0.130 to 0.046)	0.354	−0.032 (−0.123 to 0.060)	0.495
Recurrent major depression (severe)	−0.100 (−0.126 to −0.074)	<0.001	−0.058 (−0.085 to −0.030)	<0.001
Recurrent major depression (moderate)	−0.049 (−0.069 to −0.029)	<0.001	−0.002 (−0.024 to 0.019)	0.829
Single episode major depression	−0.003 (−0.029 to 0.023)	0.809	0.016 (−0.011 to 0.043)	0.236

Abbreviations: CI, confidence interval; CRP, C-reactive protein.

^aFull model adjusted for age, gender, Townsend deprivation score, educational status, current depressive symptoms.

^bLinear regression; omitted reference group was the mood disorder control group and serum CRP quintile 1; coefficients are in z-score units (higher = better performance).