Table 4.

Multiple regression results for the relationship between pairs matching z-score, mood disorder group and serum CRP level quintile before and after adjusting for confounders.

	Unadjusted model		Fully adjusted modela
	Coefficient (95% CI)	p-Value	Coefficient (95% CI)	p-Value
Pairs matching z-scoreb
Serum CRP level quintile
2	0.021 (0.000 to 0.043)	0.055	0.032 (0.010 to 0.055)	0.005
3	0.030 (0.008 to 0.052)	0.008	0.054 (0.031 to 0.077)	<0.001
4	0.029 (0.007 to 0.051)	0.010	0.060 (0.037 to 0.083)	<0.001
5	0.027 (0.005 to 0.049)	0.019	0.066 (0.042 to 0.089)	<0.001
Bipolar disorder type I	−0.180 (−0.272 to −0.088)	<0.001	−0.163 (−0.258 to −0.067)	0.001
Bipolar disorder type II	−0.074 (−0.169 to 0.022)	0.130	−0.065 (−0.164 to 0.034)	0.200
Recurrent major depression (severe)	−0.104 (−0.131 to −0.076)	<0.001	−0.095 (−0.125 to −0.065)	<0.001
Recurrent major depression (moderate)	−0.029 (−0.050 to −0.007)	0.009	−0.025 (−0.048 to −0.002)	0.036
Single episode major depression	0.032 (0.004 to 0.060)	0.026	0.027 (−0.002 to 0.056)	0.070

Abbreviations: CI, confidence interval; CRP, C-reactive protein.

^aFull model adjusted for age, gender, Townsend deprivation score, educational status, current depressive symptoms.

^bLinear regression; omitted reference group was the mood disorder control group and serum CRP quintile 1; coefficients are in z-score units (higher = better performance).