Fig. 2C.

The interaction between APOA2 -265 T>C polymorphism and the DTAC: FRAP (a), TRAP (b), TEAC (c), and ORAC (d) intake on serum LDL level. According to the median dietary TAC the participants were dichotomized into “high” and “low” categories (≤, > of median), FRAP (≤15.94, 15.95 > mmol Fe²⁺/d); TRAP (≤8.25, 8.26 > mmol TE/d); TEAC (≤7.46, 7.47> mmol TE/d); ORAC (≤27296.21, 27296.22> μmol TE/d). P*; crude, P1; model 1, and P2; model 2. P*-values for the interaction terms between dietary TAC intake (as dichotomous) and the APOA2 polymorphism in each population were obtained in the General Linear Model (Two-Way ANOVA). The P1 value of the interaction (Model 1) is adjusted for sex (as categorical), supplement use (as categorical), PUFA, fiber, and total energy intake (as continuous). In model 2, in addition to the variables of model 1, it was also adjusted based on the variables of age (as continuous), BMI (as continuous), smoking (as categorical), and lipid-lowering medicine (as categorical) using the ANCOVA test. Independent Samples t-test was used to compare the mean serum LDL level between low and high DTAC intake base on rs5082 genotypes. The bars indicate mean (SD).