Fig. 2D.

Interaction between the APOA2 polymorphism and the DTAC: FRAP (a), TRAP (b), TEAC (c), and ORAC (d) intake with regard to serum HDL level. According to the median dietary TAC the participants were dichotomized into “high” and “low” categories (≤, > of median), FRAP (≤15.94, 15.95 > mmol Fe²⁺/d); TRAP (≤8.25, 8.26 > mmol TE/d); TEAC (≤7.46, 7.47> mmol TE/d); ORAC (≤27296.21, 27296.22> μmol TE/d). P*; crude, P1; model 1, and P2; model 2. P*-values for the interaction terms between dietary TAC intake (as dichotomous) and the APOA2 polymorphism were obtained with General Linear Model (Two-Way ANOVA). The P1 value of the interaction (Model 1) is adjusted for age (as continuous) sex (as categorical), smoking (as categorical), and physical activity (as categorical). In model 2, in addition to the variables of model 1, it was also adjusted based on the variables of supplement use (as categorical), lipid-lowering medicine (as categorical), BMI (as continuous), and total energy intake (as continuous) using the ANCOVA test. In the stratified analysis by APOA2 genotypes, P-values for mean comparisons of serum HDL level between two categories of antioxidant intake were estimated by Independent Samples t-test. Bars indicate SD.