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. Author manuscript; available in PMC: 2021 Sep 17.
Published in final edited form as: Nature. 2021 Mar 17:10.1038/s41586-021-03351-3. doi: 10.1038/s41586-021-03351-3

Extended Data Fig. 7. Preexisting memory T cells retain functional potency following heterologous prime-boost immunization.

Extended Data Fig. 7.

a, 60 days after LCMV, P14 immune chimeras were subjected to heterologous prime-boost (HPB) regimen. Ex vivo functionality of memory P14 CD8+ T cells in various tissues was compared and not statistically significant (p > 0.05) between n = 4-5 mice (n varies by tissue) receiving HPB and n = 5 age-matched control mice from one of two independent experiments with similar results. Statistical significance was determined by two-tailed Mann-Whitney U test. Data are presented as mean values +/− SEM.