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. 2021 Apr 20;16(4):e0250044. doi: 10.1371/journal.pone.0250044

Table 4. Factors associated with CT or NG infection in women in Kigali, Rwanda (N = 579).

Total (N = 579) CT-infected (N = 98) CT-uninfected (N = 481) p-value NG-infected (N = 152) NG-uninfected (N = 427) p-value
Demographics n /mean Col%/SD n /mean Row%/SD n /mean Row% /SD   n /mean Row%/SD n /mean Row%/SD  
Age, continuous (years) 28.7 7.2 25.6 6.1 29.3 7.2 <0.0001 26.8 6.3 29.4 7.4 <0.0001
Referrer                        
    Radio Advert 284 49% 37 13% 247 87% 0.014 67 24% 217 76% 0.153
    Friends/Walk-in/Pharmacy/Contact Partner/Internet 295 51% 61 21% 234 79%   85 29% 210 71%  
Living and Marital Status                        
    Married and Cohabiting 268 46% 34 13% 234 87% 0.012 60 22% 208 78% 0.050
    Single or Divorced/Separated/Widow 311 54% 64 21% 247 79%   92 30% 219 70%  
Education Level                        
    None 25 4% 2 8% 23 92% 0.513 9 36% 16 64% 0.001
    Primary 242 42% 38 16% 204 84%   81 33% 161 67%  
    Secondary 246 42% 46 19% 200 81%   54 22% 192 78%  
    Higher 66 11% 12 18% 54 82%   8 12% 58 88%  
Employment Status                        
    Full-time employment 199 34% 30 15% 169 85% 0.383 39 20% 160 80% 0.008
    Part-time/Student/Jobless 379 66% 68 18% 311 82%   113 30% 266 70%  
Sexual behaviors                        
Number of partners in last 30 days                        
    None or one partner 444 83% 70 16% 374 84% 0.112 95 21% 349 79% <0.0001
    More than one partner 88 17% 20 23% 68 77%   43 49% 45 51%  
Condom use during vaginal sex in the last 3 months                        
    No partners or always used condoms 35 7% 6 17% 29 83% 0.259 4 11% 31 89% <0.0001
    Sometimes 163 31% 34 21% 129 79%   66 40% 97 60%  
    Never 334 63% 50 15% 284 85%   68 20% 266 80%  
Number of days since sexual contact you suspect STI was acquired from                        
    < = 8 46 9% 8 17% 38 83% 0.066 15 33% 31 67% 0.003
    9–16 78 15% 20 26% 58 74%   31 40% 47 60%  
    > = 17 409 77% 61 15% 348 85%   92 22% 317 78%  
Number of children under 18, continuous 1.3 1.3 1.0 1.1 1.3 1.3 0.026 1.2 1.1 1.3 1.3 0.600
Number of additional children desired, continuous 1.4 1.1 1.6 1.1 1.4 1.2 0.040 1.3 1.0 1.4 1.2 0.279
Pregnant                        
    Yes 48 8% 8 17% 40 83% 0.947 11 23% 37 77% 0.569
    No 528 92% 90 17% 438 83%   141 27% 387 73%  
Want more children in next two years                        
    Yes 125 23% 20 16% 105 84% 0.666 33 27% 88 73% 0.821
    No 419 77% 74 18% 345 82%   106 26% 298 74%  
Family planning method among women not pregnant and do not want more children in next two years                        
    Non-Hormonal Method (IUD/Condom/Tubal Ligation/Natural Method) or No Method 268 66% 47 18% 221 82% 0.498 56 21% 212 79% 0.001
    Hormonal Implant 50 12% 9 18% 41 82%   24 48% 26 52%  
    Injectable 48 12% 5 10% 43 90%   16 33% 32 67%  
    Pills 40 10% 9 23% 31 78%   12 30% 28 70%  
Family planning method and pregnancy composite                        
    Pregnant 48 8% 8 17% 40 83% 0.979 11 23% 37 77% 0.003
    Hormonal method (implant, injectable, pills) 139 24% 23 17% 116 83%   52 37% 87 63%  
    Non-Hormonal (IUD/Condom/ Tubal Ligation/Natural Method) or No Method 388 67% 67 17% 321 83%   89 23% 299 77%  
Self-reported symptoms                        
Vaginal discharge                        
    Yes 475 82% 78 16% 397 84% 0.412 123 26% 352 74% 0.704
    No 101 18% 20 20% 81 80%   28 28% 73 72%  
Genital itching                        
    Yes 320 56% 52 16% 268 84% 0.732 57 18% 263 82% <0.0001
    No 254 44% 44 17% 210 83%   92 36% 162 64%  
Dysuria                        
    Yes 266 46% 44 17% 222 83% 0.793 75 28% 191 72% 0.306
    No 311 54% 54 17% 257 83%   76 24% 235 76%  
Genital ulcer                        
    Yes 64 11% 9 14% 55 86% 0.489 9 14% 55 86% 0.020
    No 508 89% 89 18% 419 82%   140 28% 368 72%  
Number of days with symptoms                        
    1–5 72 13% 16 22% 56 78% 0.170 24 33% 48 67% 0.003
    6–10 77 14% 17 22% 60 78%   27 35% 50 65%  
    11–21 131 24% 18 14% 113 86%   40 31% 91 69%  
    >21 257 48% 37 14% 220 86%   48 19% 209 81%  
Laboratory and physical exam                        
HIV Status                        
    Positive 75 13% 8 11% 67 89% 0.121 34 45% 41 55% <0.0001
    Negative 504 87% 90 18% 414 82%   118 23% 386 77%  
RPR Result                        
    Positive 46 8% 10 22% 36 78% 0.401 21 46% 25 54% 0.002
    Negative 522 92% 88 17% 434 83%   128 25% 394 75%  
Trichomonas                        
    Positive 72 13% 18 25% 54 75% 0.038 18 25% 54 75% 0.818
    Negative 491 87% 75 15% 416 85%   129 26% 362 74%  
Candida                        
    Positive 118 21% 12 10% 106 90% 0.035 13 11% 105 89% <0.0001
    Negative 437 79% 80 18% 357 82%   132 30% 305 70%  
Bacterial vaginosis                        
    Positive 113 21% 25 22% 88 78% 0.062 47 42% 66 58% <0.0001
    Negative 438 79% 65 15% 373 85%   96 22% 342 78%  
Vaginal Inflammation or Discharge                        
    Yes 469 87% 75 16% 394 84% 0.232 116 25% 353 75% 0.076
    No 69 13% 15 22% 54 78%   24 35% 45 65%  
Endocervical Inflammation or Discharge                        
    Yes 262 49% 55 21% 207 79% 0.010 88 34% 174 66% <0.001
    No 275 51% 35 13% 240 87%   52 19% 223 81%  
Genital Ulcer                        
    Yes 48 9% 9 19% 39 81% 0.652 12 25% 36 75% 0.857
    No 481 91% 78 16% 403 84%   126 26% 355 74%  

Not significant not shown include: Self-reported symptoms anal discharge, anal ulcer, anal warts, and sore throat; genital exam results non-menstrual bleeding (cervix and vagina), condyloma/warts (cervix and vagina), inguinal adenopathy >1cm unilateral and bilateral, adnexal tenderness and adnexal mass.

IUD: intrauterine device; RPR: Rapid plasma reagin; CI: Confidence interval; STI: Sexually transmitted disease; NG: Neisseria gonorrhoeae, CT: Chlamydia trachomatis