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. 2021 Apr 20;16(4):e0250044. doi: 10.1371/journal.pone.0250044

Table 5. Univariate and multivariate analysis of factors associated with CT or NG infection in women in Kigali, Rwanda (N = 579).

  CT infection NG infection
  cPOR 95% CI p-value aPOR 95% CI p-value cPOR 95% CI p-value aPOR 95% CI p-value
Demographics                                
Age (per year increase) 0.91 0.88 0.95 <0.0001 0.90 0.86 0.94 <0.0001 0.95 0.92 0.97 < .001 0.93 0.89 0.97 <0.001
Referrer                                
    Radio Advert ref               ref              
    Friends/Walk-in/Pharmacy/Contact Partner/Internet 1.74 1.11 2.72 0.015         1.31 0.91 1.90 0.150        
Living and Marital Status                                
    Married and Cohabiting ref               ref              
    Other 1.78 1.13 2.80 0.012         1.46 1.00 2.13 0.048        
Education Level                                
    None/Primary ref               2.09 1.44 3.04 0.000 2.13 1.30 3.48 0.003
    Secondary/Higher 1.30 0.83 2.01 0.248         ref       ref      
Employment Status                                
    Full-time employment ref               ref       ref      
    Part-time/Student/Jobless 1.23 0.77 1.96 0.383         1.76 1.16 2.66 0.008 1.95 1.12 3.39 0.019
Sexual behaviors                                
Number of partners in last 30 days                                
    None or one partner ref               ref              
    More than one partner 1.56 0.89 2.75 0.119         3.53 2.19 5.69 <0.0001        
Condom use during vaginal sex in the last 3 months                                
    No partners or always used condoms 1.17 0.46 2.97 0.741         0.48 0.15 1.5 0.207 0.74 0.22 2.41 0.611
    Sometimes 1.49 0.92 2.42 0.107         2.75 1.81 4.18 <0.0001 1.79 1.07 2.98 0.025
    Never ref               ref       ref      
Number of days since sexual contact you suspect STI was acquired from                                
    0–8 1.20 0.53 2.69 0.666         1.66 0.87 3.16 0.126        
    9–16 1.96 1.1 3.49 0.022         2.29 1.36 3.87 0.002        
    > = 17 ref               ref              
Number of children under 18 (per child increase) 0.82 0.69 0.99 0.037         0.96 0.84 1.10 0.594        
Number of additional children desired (per child increase) 1.22 1.02 1.45 0.027         0.92 0.79 1.07 0.274        
Family planning method and pregnancy composite                                
    Pregnant 0.96 0.43 2.14 0.915         1.00 0.49 2.03 0.999 1.30 0.57 2.99 0.532
    Hormonal method (implant, injectable, pills) 0.95 0.56 1.59 0.837         2.01 1.32 3.05 0.001 1.73 1.02 2.94 0.040
    Non-Hormonal (IUD/Condom/Tubal Ligation/Natural Method) or No Method ref               ref       ref      
Self-reported symptoms                                
Vaginal discharge                                
    Yes ref               ref              
    No 1.26 0.73 2.18 0.408         1.10 0.68 1.78 0.692        
Genital itching                                
    Yes ref               ref       ref      
    No 1.08 0.69 1.68 0.738         2.62 1.79 3.84 <0.0001 2.54 1.55 4.17 0.0002
Dysuria                                
    Yes ref               1.21 0.84 1.75 0.303        
    No 1.06 0.68 1.64 0.796         ref              
Genital ulcer                                
    Yes ref               ref       ref      
    No 1.30 0.62 2.73 0.489         2.33 1.12 4.84 0.024 2.52 1.09 5.80 0.030
Number of days with symptoms                                
    1–10 1.72 1.06 2.78 0.027 1.76 1.07 2.88 0.026 1.76 1.16 2.68 0.008 1.78 1.05 3.00 0.032
    11 or more ref       ref       ref       ref      
Laboratory and physical exam                                
HIV Status                                
    Positive ref               2.73 1.66 4.47 <0.0001 2.05 1.10 3.83 0.024
    Negative 1.83 0.85 3.96 0.124         ref       ref      
RPR Result                                
    Positive 1.37 0.66 2.88 0.401         2.58 1.41 4.7 0.002        
    Negative ref               ref              
Trichomonas                                
    Positive 1.85 1.03 3.32 0.041         ref              
    Negative ref               1.06 0.60 1.88 0.838        
Candida                                
    Positive ref               ref       ref      
    Negative 1.98 1.04 3.77 0.038         3.56 1.89 6.69 <0.0001 2.20 1.11 4.36 0.024
Bacterial vaginosis                                
    Positive 1.63 0.98 2.72 0.063         2.63 1.67 4.15 <0.0001 1.89 1.07 3.34 0.028
    Negative ref               ref       ref      
Vaginal Inflammation OR Discharge                                
    Yes ref               ref              
    No 1.47 0.79 2.75 0.2201         1.67 0.97 2.86 0.063        
Endocervical Inflammation or Discharge                                
    Yes 1.83 1.15 2.91 0.010         2.17 1.46 3.23 0.000 1.80 1.11 2.93 0.018
    No ref               ref       ref      
Genital Ulcer                                
    Yes 1.19 0.56 2.56 0.649         ref              
    No ref               1.06 0.53 2.10 0.875        

IUD: intrauterine device; aPOR: Adjusted prevalence odds ratio; cPOR: Crude prevalence odds ratio; RPR: Rapid plasma reagin; CI: Confidence interval; STI: Sexually transmitted disease; NG: Neisseria gonorrhoeae, CT: Chlamydia trachomatis