Figure 2.

This panel illustrates three cases with KIAA1549^Ex16‐BRAF^Ex9 fusion confirmed by sequencing (C,G,M) and correlates the radiological‐histological features with the corresponding sequencing analysis of IDH1: glioblastoma (A–D): (A) T1‐weighted MRI shows an insular lesion with ring‐enhancement; (B) histological features showing hypercellularity, cellular atypia and vessels proliferation; (D) sequencing analysis showing IDH1 gene wild‐type; oligoastrocytoma (E–H): (E) T1‐weighted MRI with contrast reveals a hypointense nonenhancing parietal lesion. (F) Histological examination shows an oligoastrocytoma grade II with R132H mutation in IDH1 gene (H); ganglioglioma (I–N): (I) T1‐weighted MRI shows a small enhancing cortical lesion (arrow) composed of a mixed population of glial and mature ganglion cells (L) and IDH1 wild‐type gene (N).