Table 3.

Clinical and pathological data of diffuse gliomas with KIAA1549^Ex16‐BRAF^Ex9 fusion gene and their association with IDH mutations and/or 1p/19q loss. Abbreviations: A = astrocytoma; GBM = glioblastoma; IDH = isocitrate dehydrogenase; Mut = mutant; NA = not analyzed; OA = oligoastrocytoma; OO = oligodendroglioma; WHO = World Health Organization; WT = wild type.

Case	Sex	Age (years)	Diagnosis*	Location	KIAA1549 Ex16‐ BRAF Ex9	IDH1 fusion	IDH2	1p19q loss	Follow‐up (months)
1	Female	52	GBM	Insular	Yes	WT	NA	NA	8 (dead)
2	Male	50	OOII	Temporal	Yes	Mut†	NA	Yes	72 (alive)
3	Female	32	OA II	Parietal	Yes	Mut†	NA	Yes	70 (alive)
4	Male	45	OO III	Frontal	Yes	Mut†	NA	NA	70 (alive)
5	Female	50	OO III	Multifocal	Yes	Mut†	NA	Yes	48 (alive)
6	Female	35	OA II	Frontal	Yes	Mut†	NA	Yes	47 (alive)
7	Male	34	OO II	Frontal	Yes	Mut†	NA	Yes	36 (alive)
8	Female	53	OO III	Frontal	Yes	NA	NA	NA	24 (dead)
9	Female	33	OA III	Hemispheric	Yes	Mut†	WT	No	45 (alive)
10	Female	32	A II	Hemispheric	Yes	Mut†	WT	No	48 (dead)
11	Female	53	OO II	Hemispheric	Yes	Mut†	WT	No	21 (alive)
12	Male	46	OO II	Hemispheric	Yes	Mut†	WT	Yes	29 (alive)
13	Female	43	OO III	Hemispheric	Yes	WT	Mut‡	No	19 (dead)
14	Male	44	OO III	Frontal	Yes	WT	WT	No	16 (dead)
15	Male	43	OO III	Temporal‐occipital	Yes	WT	WT	No	26 (dead)
16	Male	41	OO III	Temporal	Yes	WT	WT	No	13 (alive)
17	Female	73	OO III	Hemispheric	Yes	WT	WT	No	46 (dead)

^* Roman numerals refer to WHO histological grade.

^† IDH1^R132H

^‡ IDH2^R172K