Table 1.

Clinicopathological characteristics of patients with Huntington's disease and control subjects. Abbreviations: NBB = Netherlands Brain Bank number; M = male; F = female; CTD = clock time of death; MD = month of death; PMD = post‐mortem delay; FIX = fixation time (in days); CAG = mutant Huntingtin CAG repeat length; HD = Huntington's disease; NA = not assessed; SEM = standard error of mean; Vonsattel = HD disease staging according to Vonsattel et al's criteria (36)

	NBB		Sex	Age	Onset	CTD	MD	PMD	Fix	CAG	CSF pH	Vonsattel	Cause of death
Patients	99‐108	HD‐1	M	49	40	9:15	8	5:45	49	51	6.30	3	Cachexia
	03‐047	HD‐2	F	50	35	18:25	6	5:40	55	47	6.46	2	Pneumonia
	92‐105	HD‐3	M	54	41	9:55	12	3:50	80	ND	ND	2	Sudden death
	95‐060	HD‐4	M	57	42	3:30	6	7:30	53	46	6.46	3	Cachexia
	08‐044	HD‐5	M	59	50	18:10	5	5:05	52	44	6.90	1	Legal euthanasia
	01‐128	HD‐6	M	61	39	10:55	11	10:25	48	43	6.57	2	Pneumonia
	98‐047	HD‐7	F	67	56	10:10	4	6:05	41	45	6.70	1	Legal euthanasia
	99‐120	HD‐8	M	79	54	19:00	10	6:15	34	44	6.45	4	Pneumonia
	00‐109	HD‐9	F	80	58	7:15	10	22:30	49	41	6.54	2	Pneumonia
Mean				62	46	11:50	8	8:07	51	45	6.55	2
SEM				4	3	1:49	1	1:53	4	1	0.06	0.3
Controls	99‐080	C‐1	M	56	—	20:40	3	12:20	112	—	ND	—	Heart failure
	97‐127	C‐2	F	49	—	3:30	4	13:30	165	—	ND	—	Cervix carcinoma
	98‐027	C‐3	M	54	—	9:00	12	8:00	59	—	ND	—	Hepatocellular carcinoma
	99‐141	C‐4	M	44	—	10:00	7	7:00	149	—	ND	—	Cardiac infarction
	98‐127	C‐5	M	56	—	15:45	8	5:25	35	—	6.55	—	Cardiac infarction
	92‐042	C‐6	M	61	—	21:00	4	13:50	52	—	7.20	—	Esophageal carcinoma
	98‐161	C‐7	F	61	—	8:06	8	8:54	87	—	ND	—	Ovarium carcinoma
	93‐060	C‐8	M	79	—	14:00	2	3:00	53	—	ND	—	Leaking aorta prosthesis
	00‐022	C‐9	F	83	—	7:45	2	21:00	34	—	6.52	—	Cardiac infarction
Mean				60	—	12:11	6	10:19	83	—	6.76	—
SEM				4	—	2:00	1	1:48	16	—	0.13	—
Level of significance				0.73*	—	0.88†	0.71†	0.08*	0.14*	—	—	—

^† Mardia–Watson test.

^* Mann–Whitney U‐test.