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Variable amounts of α‐synuclein (B) and α‐synuclein phosphorylated at Ser129 (E, red) accumulate at the periphery of β‐amyloid plaques (A, D, green). Rab3a (G, green) is found in dystrophic neurites surrounding β‐amyloid plaques (H, red). Similarly, APP (J, green) accumulates in the vicinity of amyloid deposits (K, red). Nuclei are stained in blue (DRAQ5). APP/PS1 mice aged 12/14 months. A–F, bar = 40 µm; G–L, bar = 20 µm.
