Table 1.
Characteristics of the TASTY Cohort.
| Valid N | All | Male | Female | P‐value |
|---|---|---|---|---|
| 603 | 388 (64.3%) | 215 (35.7%) | ||
| Age, years ± SD | 62.7 ± 19.1 | 59.6 ± 18.8 | 68.2 ± 18.6 | <0.0001 |
| <65 years | 298 | 219 (73.5%) | 79 (26.5%) | <0.0001 |
| ≥65 years | 305 | 169 (55.4%) | 136 (44.6%) | NS |
| BMI, kg/m2 ± SD | 27.4 ± 6.15 | 27.1 ± 5.86 | 27.8 ± 6.65 | NS |
| Cause of death | ||||
| Disease | 59.1% | 59.6% | 58.1% | NS |
| Accident | 27.0% | 26.2% | 28.4% | NS |
| Suicide | 12.0% | 12.4% | 11.2% | NS |
| Homicide | 0.5% | 0.8% | 0% | NS |
| Unknown | 1.5% | 1.0% | 2.3% | NS |
| Dementia Status | ||||
| AD | 1.0% | 0.5% | 1.9% | NS |
| Dementia | 2.7% | 1.8% | 4.2% | NS |
| Memory problems | 1.7% | 1.3% | 2.3% | NS |
| Parkinson's disease | 0.2% | 0.3% | 0% | . |
| Neuropathological lesions | ||||
| SP | 31.1% | 24.9% | 41.5% | <0.0001 |
| Non neuritic | 9.9% | 8.7% | 12.1% | NS |
| Neuritic | 19.1% | 15.1% | 26.1% | 0.001 |
| Diffuse | 3.7% | 3.9% | 3.4% | NS |
| Primitive | 6.2% | 4.8% | 8.7% | 0.02 |
| Classic | 14.7% | 11.2% | 20.8% | 0.001 |
| Burnt out | 4.4% | 3.9% | 5.3% | NS |
| SP coverage ≤ 1.05% | 15.5% | 13.6% | 18.6% | 0.02 |
| SP coverage > 1.05% | 15.5% | 11.0% | 23.0% | <0.0001 |
| NFT | 42.1% | 35.3% | 54.3% | <0.0001 |
AD = Alzheimer's disease; BMI = body mass index; NFT = neurofibrillary tangles; NS = nonsignificant; N = number of cases SP = senile plaques; SD = standard deviation; TASTY = Tampere Autopsy Study.