. Author manuscript; available in PMC: 2021 Apr 20.

Published in final edited form as: J Alzheimers Dis. 2021;79(2):895–903. doi: 10.3233/JAD-201267

Table 3. Comparison of plasma spermidine levels between D-CAA and CU adults.

D-CAA MC	CU-1	CU-2	p	p^adj	p^a	p^b
N=9	N=7	N=100
0.082±0.038	0.177±0.029	0.195±0.054	<.0001	<.0001	.008	<.0001

Plasma spermidine levels (presented in mean±SD, μM) in D-CAA MCs were compared with plasma spermidine levels in cognitively unimpaired younger adults (CU-1) and cognitively unimpaired older adults (CU-2). p and p^adj represent univariate p-values before and after adjusting for age, sex and APOE ε4 carrier status. p^a and p^b represent pairwise comparisons between D-CAA MC and CU-1, D-CAA MC and CU-2, respectively.