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. 2021 Apr 13;2021:6662156. doi: 10.1155/2021/6662156

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Copyright © 2021 Longcheng Shang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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SS-31 regulated STAT1 and STAT3 to govern macrophage polarization. (a, b) Immunoblot analysis of STAT1 and p-STAT1 (Tyr701) in Raw264.7 treated with LPS with or without SS-31. (c, d) Immunoblot analysis of STAT3 and p-STAT3 (Tyr705) in Raw264.7 treated with LPS with or without SS-31. (e, f) Immunoblot analysis of STAT1 and p-STAT1 (Tyr701) in the liver after IRI with SS-31 pretreatment (n = 4 per group). (g, h) Immunoblot analysis of STAT3 and p-STAT3 (Tyr705) in the liver after IRI with SS-31 pretreatment (n = 4 per group). Data are mean ± SEM, ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, and ^∗∗∗∗p < 0.0001 by unpaired Student's t-test.